           |
ALUMINIUM (Al)
is commonly ingested with food, medicine and
water. Previously, aluminum was considered virtually
non-absorbable and was thus freely used in a variety of food
additives and over-the-counter drugs such as antacids. New
research suggests that Al can cause neurological changes such as
seen in Alzheimer's and Parkinson's disease, and dialysis
dementia. Al can bind to DNA, resulting in abnormal
neurofibrillary tangles in the brain. Al inhibits the enzyme,
hexokinase. It is absorbed in the intestine and excreted via the
kidney. In persons with abnormal kidney function, Al is
deposited in the bones. Toxicity symptoms include ataxia, colic,
and GI irritation. Al is widely found in foods and water. Hair:
elevated levels reflect long-term exposure and increased tissue
storage. THERAPEUTIC CONSIDERATION:
Chelation therapy is
recommended to reduce levels dramatically. Support digestive and
kidney function. As soon as digestive functions are properly
supported, the elimination of aluminum increases and the
intestinal absorption decreases. Check calcium tissue levels. An
inadequate calcium supply or calcium absorption problems
facilitate the absorption of aluminum.
ARSENIC(As)
All the biochemical actions of arsenic are
attributed to its trivalent forms, widely found in polluted
environments. Inorganic arsenic, or arsenite, does accumulate in
tissues and ranks second among heavy metals causing death.
Arsenite rapidly leaves the blood to be deposited in vital
organs and tissues such as hair, skin and nails. Symptoms of
toxicity have been associated with alopecia, confusion,
constipation, delayed wound healing, dermatitis, diarrhea,
drowsiness, edema, fatigue, muscle pains, numbness, seizures,
and weakness. Hematological, renal or pancreatic dysfunction may
be observed. Chronic arsenic exposure is known to cause anemias,
bone marrow depression, cancers of the respiratory tract, skin
and neurological problems. Ingestion of relatively large amounts
of soluble arsenic compounds, especially on an empty stomach,
affect the myocardium, causing death. Long-term exposure to
small amounts of arsenic increase hair and urine levels; however
considerate chronic exposure results in hair loss. Hair or nails
are known to be used in forensic medicine to establish
long-term, chronic exposure and slow-rate poisoning. Blood
levels do not increase until toxicity has been reached. Urine
measurements are used to monitor chelation therapy. THERAPEUTIC
CONSIDERATION:
Chelation therapy is the treatment of choice to
get rid of acute and chronic deposits. In addition cases of
chronic exposure respond well to antioxidant therapy, especially
ascorbic acid, calcium ascorbate, all tocopherols (vit. E) and
an increased intake of sulfur-containing amino acids and vit.
B6. Arsenic suppresses iodine and selenium.
BARIUM (Ba)
is not readily absorbed; however intestinal
dysfunctions support the uptake. Barium is then distributed in
very low concentration in soft tissues. It appears to inhibit
the calcium absorption and has properties that are similar to
lead and cadmium. High Barium levels are almost always an
indication of heavy metal toxicity in the tissues, which isn’t
always reflected in the hair. A
urine
challenge test is recommended. Barium X-ray
techniques can increase tissue levels. SOURCES: drinking water.
The EPA allows a maximum level of 1PPM. THERAPEUTIC
CONSIDERATION: Digestive support to reduce intestinal uptake.
Zinc and antioxidants, including selenium are recommended to
normalize barium levels.
BORON (B)
is considered a catalytic element that has
considerable involvement in glycogen synthesis in the liver.
Lewin and Chen stated that boron affects the activity of
numerous enzymes, might have co enzymatic function but can also
inhibit some enzymes such as pyridine and chymotrypsin. Oral
administration of boron has a low toxicity, but excessive intake
of boron or boron compounds can interfere with the calcium and
magnesium metabolism, causing boron to be stored in bone. Dental
enamel varies widely in content, and the concentration is
similar to that of hair and soft tissue. Boron is rapidly
absorbed and excreted via the urine. Toxicity symptoms include
nausea, vomiting, diarrhea, dermatitis, lethargy and induces
riboflavonuria. THERAPEUTIC CONSIDERATION: check calcium,
magnesium, phosphorus levels. Increase riboflavin and pyridoxin
intake to reduce or abolish toxic effects of boron.
CADMIUM (Cd)
is toxic to virtually every system of the body.
It has been implicated in renal disease, prostatic carcinoma and
other cancers, hypertension, anemia, itai-itai disease and
anemias. It inhibits enzyme and nutrient utilization, and is
readily stored in the kidney where it competes with zinc for
binding sites in various enzymes and other proteins. Zinc,
vitamin C, iron and/or calcium intake can partially protect
against cadmium overload. Smoke increases the susceptibility to
toxicity. Acute poisoning causes severe pulmonary and bronchial
irritation. SOURCE: pollution, smoking. Hair analysis reflects
long-term, chronic exposure and tissue overload, and tissue
levels increase with age. THERAPEUTIC CONSIDERATION:
Chelation therapy
is the treatment of choice. Antioxidant therapy with emphasis on
vitamin C also helps. Zinc and vitamin B6; increased amino acid
intake. Water contamination and amalgam fillings are recognized
sources of cadmium toxicity.
CALCIUM (Ca)
The major fraction of body calcium resides in bone,
with calcium being the most abundant mineral in humans. It is
essential for muscular and neurological functions; influences
hormone secretion, and is involved in immune/oxidant responses.
Symptoms of calcium excess include anorexia, aphasia, ataxia,
depressed deep tension reflexes, irritability, memory impairment,
muscle weakness and psychosis. The RDA is 800-1200mg/day. SOURCES:
dairy products, leafy vegetables, citrus fruits, canned fish with
edible bones and molasses. Hair calcium levels reflect long-term
nutritional intake, and metabolic conditions. Elevated hair levels
generally indicate maldistribution of calcium out of bones and into
soft tissues, reflecting a masked deficiency. Perming, dyeing or
bleaching of hair falsely elevate hair calcium levels and are not
indicators of the calcium status. THERAPEUTIC CONSIDERATION: check
for calcium deficiency symptoms such as nightly spasms, menstrual
problems, nervousness, irritability, digestive disorders and
insomnia. Increased allergic tendencies and milk intolerance may be
present. To normalize calcium levels, increase activity level,
reduce fat intake and check phosphorus levels. High fat or
phosphorus intake (meat, sugars) can interfere with the calcium
absorption. If calcium and magnesium levels are high, increase the
intake of both and vitamin D. Support digestive function to further
increase absorption.
CHROMIUM (Cr)
is an essential trace element that is required for
the sugar and fat metabolism and is part of the glucose tolerance
factor. Deficiency conditions are atherosclerotic plaque, elevated
LDL cholesterol levels, increased insulin need, impaired glucose
tolerance and a reduced stress response. Deficiency causes are diets
rich in highly processed foods, alcoholism, malabsorption, and
insufficient intake of B-vitamins. SOURCES: whole grains, brewer's
yeast, wheat germ, meat and cheeses. Hair is a reflection of
long-term nutritional intake and low levels indicate an increased
dietary need for chromium. THERAPEUTIC CONSIDERATION: increase
chromium and B-vitamin intake.
COBALT
(Co)
is
part of the Vitamin B12 molecule and is necessary for Vitamin B12
activity and function. Cobalt, which is mainly stored in the liver,
activates numerous enzymes, and is excreted in bile. A low dietary
intake inhibits fetal development. SOURCES: all animal products,
including all meats, fish, cheese, brewer's yeast and yeast
extracts. Strict vegetarians (vegans) and those who lack intrinsic
factor risk vitamin B12 and cobalt deficiency. THERAPEUTIC
CONSIDERATION: increase vitamin B12 intake and/or consumption of
cobalt-rich foods.
COPPER (Cu)
is an important metallo-enzyme. It is an activator of
dopamine beta-hydroxylase and essential element for proper adrenal
function. The liver is the main organ for storage and excretion.
Copper is tightly bound to the protein ceruloplasmin, to amino acids
esp histidine, threonine and glutamine, and to albumin. These amino
acids and albumin are important for the copper transport between the
liver and various peripheral tissues. Toxicity symptoms include
nausea, diarrhea, vomiting, discoloration of skin and hemolytic
anemia. High copper levels are often accompanied by zinc deficiency
and long-term estrogen therapy can increase hair copper levels,
causing emotional instability and depression. High copper levels
increase the toxic effect of selenium and suppress iron absorption.
Excessive exposure and inhalation of industrial copper dust causes
contact dermatism cardiomyopathy, liver and kidney damage. SOURCES:
whole grains, shellfish, nuts, organ meats, eggs, cocoa, chocolate,
Brewer's yeast and copper-rich drinking water. Copper IUDs have also
caused elevated copper levels. THERAPEUTIC CONSIDERATION: In
Wilson's disease, copper levels are low in peripheral tissues such
as hair. To normalize levels, evaluate iron, manganese, zinc and
molybdenum levels. Vitamin C increases the copper mobilization and
excretion, especially when used with amino acids and vitamin B6.
GERMANIUM (Ge)
may stimulate immune functions and demonstrate
anti-tumor and antiviral activities. However, Ge is not essential to
human health, and low levels do not reflect the need for Germanium
therapy. This trace element is not normally found in human specimen
and low levels are expected. SOURCE: found in most foods,
particularly garlic, camphor, and aloe vera. Also present in
drinking water in varying amounts, depending on location.
GOLD (Au)
has no physiological properties; however gold
compounds have been used homeopathically and for the treatment of
rheumatoid arthritis since the early 1940's, but the clinical
significance of these treatments remain unknown. Therapeutically
injected soluble gold is excreted mainly via the urine. Confirming
tests for overexposure to gold are 24 hr urine measurements. Excess
gold may produce weakness, paresthesia and skin rashes. Most foods
contain only minute amounts of gold, and the dietary intake is
<6mcg/day. Dry fruit and nuts are best sources. Gold fillings may be
another source of exposure. THERAPEUTIC CONSIDERATION: increase
intake of antioxidants and support kidney function with increased
vitamin B6 intake.
IRON (Fe)
is essential for the oxygen transport and
utilization. Iron is regulated in the body primarily by absorption
rather than by excretion. Gastrointestinal function is important in
controlling total body iron. The most common sign of deficiency is
anemia. Symptoms include fatigue, dizziness, energy loss and
decreased immune function. Predisposing factors to iron deficiency
may be excessive intake of copper, manganese, zinc, carbonates,
oxalates, phosphates, phytates, antibiotics, coffee, or heavy metal
exposure. Excessive blood loss or pregnancy can cause iron
deficiency. Daily requirements vary depending on sex, age, and
physio-logical status. The RDA is 10-18mg/day. SOURCES: liver, other
meats and green leafy vegetables. THERAPEUTIC CONSIDERATION: check
lead, copper and manganese levels. Prior to iron supplementation,
increase intake of vitamin C, B-complex and amino acid to aid
absorption.
LEAD (Pb)
Occupational and environmental exposures are the
common causes of exposure. Lead reduces the body's ability to
utilize calcium, magnesium, zinc, iron and other important
nutrients. This heavy metal greatly affects health. It is a known
cause of anemia, and children are easily affected by lead exposure.
Toxicity symptoms include abdominal pain, anorexia, anxiety,
constipation, fatigue, headaches, impaired coordination,
indigestion, irritability, muscle pains, learning and neurological
disorders, incl. tremors, severe anemias and immune deficiencies,
learning disabilities, hyperactivity and violent behavior. SOURCES:
leaded gasoline, canned goods, lead paint, newsprint, black hair
dyes and rinses (where lead is absorbed through the skin into the
blood stream and tissues), tobacco smoke, air pollution, and
contaminated water. THERAPEUTIC CONSIDERATION:
Chelation therapy
is the treatment of choice to get rid of high lead levels. Vitamin
C, sulfur-bearing amino acids and other chelating agents can
increase the urinary excretion and thus reduce toxicity and tissue
overload, including that of bones. In acute cases of exposure,
chelation treatments are recommended.
LITHIUM (Li)
is not an essential element, but is used for its
pharmacological action in psychiatric disorders. Excess intake
disturbs mineral transports across cell membranes and fluid balance
and can produce nausea, vomiting, tremors, thirst, excessive
urination, thyroid swelling, weight gain, drowsiness, confusion,
disorientation, delirium, skin eruptions, seizures, coma or death.
Some cases of irreversible kidney damage have been reported after
long-term lithium therapy. Biochemically, the action of lithium is
similar to that of sodium. Lithium is absorbed by the tubuli and
mainly excreted through the urine. THERAPEUTIC CONSIDERATION: High
levels should be confirmed with serum or plasma drawn 8 to 10 hours
after oral dose of lithium for routine monitoring of lithium therapy
or a 24-hour urine analysis.
MAGNESIUM (Mg)
is an essential element with both electrolyte and
enzyme-activator functions. Elevated hair levels of chemically
untreated hair reflect the withdrawal of magnesium from bone and
muscle, signifying a masked deficiency. Check for deficiency
symptoms such as osteoporosis, periodontal disease, muscle spasms or
twitching, nervousness, convulsions, gastrointestinal problems
including pancreatitis, and/or hormonal imbalances. The combination
of high hair magnesium and calcium levels may indicate soft tissue
calcification. Perming, dyeing or bleaching hair FALSELY elevates
levels of magnesium and other elements. THERAPEUTIC CONSIDERATION:
if blood levels are normal, increase intake of magnesium and
vitamin B6.
MANGANESE (Mn)
activates important enzymes in body tissues such as
arginase in the liver and carboxylase enzymes which regulate certain
glycolysis steps in metabolism. Toxicity is unlikely without
industrial or occupational contamination. Symptoms include anorexia,
Parkinson-like neurologic disorder such as spastic gait and
mask-like facial expression, psychiatric illnesses, mental
confusion, poor memory and poor appetite. Excess Mn can interfere
with the iron and copper absorption, and impair the vitamin B1
(thiamin) metabolism. SOURCE: liver, kidney, black tea; contaminated
drinking water. THERAPEUTIC CONSIDERATION: In untreated hair, high
levels reflect body stores due to long-term and chronic exposure. To
normalize levels, increase antioxidants, esp. vitamin C intake.
Calcium deficiency increases manganese absorption.
MERCURY (Hg)
Elemental mercury is easily converted to organic
mercury by living systems. Symptoms of poisoning include
inactivation of enzyme function, birth defects, brain damage and
other central nervous system disorders. Early symptoms of mercury
overexposure include insomnia, dizziness, fatigue, drowsiness,
weakness, depression, tremors loss of appetite, loss of memory,
nervousness, headache, dermatitis, numbness, and tingling of lips
and feet, emotional instability and kidney damage. Symptoms of acute
toxicity: loss of teeth, extreme tremor, mental and emotional
disorders, kidney failure. SOURCES: overexposure may stem from
paints, explosives, electrical apparatus, batteries, mercurial
diurectics, fungicides, fluorescent lamps, cosmetics, hair dyes,
amalgams in dentistry, contaminated seafood, and petroleum products.
THERAPEUTIC RECOMMENDATION: Hair is a reliable measure of mercury
body burdens, reflecting long-term exposure.
Chelation therapy
is known to increase urinary excretion and is by far the treatment
of choice. Oral detoxification procedures concentrate on
sulfur-bearing amino acids, vitamin B6 and selenium.
MOLYBDENUM (Mo)
serves as a co-factor for xanthine and aldehyde
oxidases. Dietary molybdenum is readily absorbed by the intestine
and is excreted in the urine and bile. SOURCES: whole grains,
legumes, leafy vegetables and organ meats. The RDA is 0.15-0.5
mg/day. Acute deficiency symptoms are unknown in humans. Excess
intake of copper, zinc, and sulfates can depress Mo-update, causing
disturbances in the uric acid cycle.Low molybdenum levels have been
associated with impotency, increased cancer susceptibility, gout,
dental caries, defects in the metabolism of sulfur-containing amino
acids,and asthma tendency. THERAPEUTIC CONSIDERATION: increase
molybdenum intake and support digestive function.
NICKEL (Ni)
toxicity has been associated with dermatitis and
pulmonary neoplasia resulting from industrial contamination. High
levels have been associated with myocardial infarct (heart attack),
and are often found in stroke victims. Nickel excess may be due to
nickel-cadmium batteries, jewelry, ceramics, cold wave permanents,
welding, and smoke. Nickel carbonyl found in cigarette and cigar
smoke is a strong carcinogen. Early symptoms of nickel exposure are
apathy, diarrhea, skin problems, insomnia, vertigo, injury to
cerebral blood vessels, vomiting and tachypnea. Toxicity symptoms
include frontal headaches, gastroenteritis, eczema, cancer of the
lung and nasal cavity. THERAPEUTIC CONSIDERATION.
Chelation therapy
is the treatment of choice to excrete the access nickel in the
urine. Elevated hair levels indicate long-term, chronic exposure and
an increased need for sulfur-bearing amino acids, pectin and
antioxidants.
PHOSPHORUS (P)
is needed for the metabolic processes of all cells,
to activate other nutrients and to form energy-storage and releasing
compounds. It is a component of several vital enzyme systems such as
adenosine triphosphate (ATP) and nucleo-proteins. Energy is stored
and released in cells by the conversion from one member of the ATP
group to another. Nucleoproteins are the major components in cell
nuclei that control cell division, reproduction and heredity.
SOURCE: all meats, fish, poultry, eggs and dairy products. The RDA
is 800mg/day. The Western diet easily supplies 1400mg/day and the
main route of excretion is via urine and feces. The metabolic action
of phosphorus resembles that of calcium. THERAPEUTIC CONSIDERATION:
Elevated hair phosphorus levels are found in the presence of
impaired glucose and protein metabolism and indicate a need for a
reduction in meat and sugar consumption, and digestive support.
Check calcium levels. High Ca and P levels are often found in
patients with milk intolerance.
POTASSIUM (K)
is an electrolyte element and a potentiator of enzyme
functions. High hair levels do not represent a systemic potassium
overload, but may reflect adrenal function and a low stress
tolerance; however the clinical significance of hair potassium
values is under investigation. THERAPEUTIC CONSIDERATION: support
adrenal function by increasing tyrosine, B-vitamin and vitamin C
intake.
SELENIUM (Se)
The biochemical role of this essential trace element
is to serve as an essential constituent of the enzyme gluthathione
peroxidase. Se is linked to cysteine residues in the protein as
selenocysteine, which is found in the cytoplasm and mitochondria of
liver, erythrocytes, platelets and other tissues. The antioxidant
role of Se parallels that of vitamin E, and Se-deficiency responds
to Vit. E supplementation. Chronic selenium deficiency has been
epidemiologically associated with certain cancers, cardiovascular
disease, cardiomyopathy and immune dysfunctions. Causes of
deficiency include inadequate selenium or cysteine intake, exposure
to toxins incl. mercury, arsenic, cadmium, PCB, etc. SOURCES: wheat
bran and germ, Brewer's yeast, garlic, whole grains, liver, kidney,
fish. The RDA is 10-200mcg/day. THERAPEUTIC CONSIDERATION: increase
intake of selenium, cysteine and vitamin E.
SILICON
(Si)
provides strength or "architectural" rigidity to
structural molecules of bone, hair, nails, skin and other organ
tissue. Research indicates that silicon reduces the degree of
atherosclerotic deposits on the aorta, and may also lower serum
cholesterol. SOURCE: widely distributed in vegetables, whole grains
and high fiber foods. There is no RDA for silicon. THERAPEUTIC
CONSIDERATION: elevated hair/nail levels of untreated hair may
reflect greater resistance to injury and better overall health. Very
high hair levels are found when the hair growth pattern is disturbed
or slowed. To normalize very high levels, support digestive
function. Silicon implants may also cause elevated levels. Ask your
physician regarding the need for treatment
SODIUM (Na)
is the most abundant extracellular electrolyte
element, which influences acid-base equilibrium and helps maintain
osmotic pressure. Sodium is readily excreted in urine and sweat and
high hair levels may be an indication of excessive sweating. High
hair levels have been linked to cystic fibrosis, but the clinical
significance of hair sodium levels is not clear. SOURCES: salt,
vegetables, fish, shellfish, meats, eggs, poultry and fish.
STRONTIUM (Sr)
possesses physiological and chemical properties
similar to calcium. Strontium is poorly absorbed by humans, and the
intestinal uptake lies between 5-25%. Of that, about 99% is found in
bone and teeth. People living in areas where high levels are found
in the water supply, show higher tissue levels. The daily intake
varies considerably from 1mg/day to 4.7mg/day, according to
geography. Strontium can interfere with the calcium metabolism,
leading to bone disorders, incl. rickets. THERAPEUTIC CONSIDERATION:
Strontium may compete with the calcium absorption and storage in
bone and teeth and when high hair strontium levels are followed by
high hair calcium level, the need for an increased calcium supply is
indicated. Algae and fibrous cellulose reduce strontium and calcium
utilization.
TIN (Sn)
is considered essential, because some studies suggest
that tin deprivation depresses growth in rats. Tin is poorly
absorbed and retained by humans and is excreted mainly in the feces.
Once tin is absorbed, both the bile and urine are routes of
excretion and the level of accumulation seems related to the intake.
Large amounts of tin can accumulate in foods that are in contact
with tin plate or are absorbed as tin fluoride from toothpaste. Tin
has a low toxicity, but tin salts are gastric irritants causing
nausea, vomiting, and diarrhea. High tin levels influence the
metabolism of several minerals, including calcium, zinc and alkaline
phosphates activities in liver and femur. Tin is a potent inducer of
heme oxygenase and thus affects heme-dependent functions. TOXICITY
SYMPTOMS: vomiting, diarrhea, abdominal cramps, loss of appetite,
tightness of chest, metallic taste in mouth, dry throat. Excessive
inhalation of tin oxide can cause Stannosis (pneumoconiosis).
THERAPEUTIC CONSIDERATION:
Chelation therapy is the
treatment of choice. Avoid toothpaste, containing stannous fluoride.
Check calcium and zinc levels.
VANADIUM (V)
the
biological function of this trace element has not been substantiated
and deficiency symptoms have not been established, although there is
evidence that this trace element influences the glucose metabolism,
the sodium/potassium transport and the adrenal catecholamine
metabolism. Vanadium appears to catalyze the oxidation of
catecholamines and inhibit cholesterol synthesis and lower
phospholipid levels. It may have anti-diabetic, weight-reducing
function and anticaries effects. SOURCE: fiber-rich foods, dill
seeds, parsley and black pepper. Vanadium is highly concentrated in
vegetable oils. THERAPEUTIC CONSIDERATION: high fiber diet, use of
vegetable oil instead of animal fats.
ZINC (Zn)
is an important metalloenzyme that is needed for
enzyme function and insulin synthesis. It is a co-factor in the
absorption and metabolism of many vitamins is needed for the
production of sex and growth hormones, wound and burn healing, and
DNA and RNA synthesis. Absorption of dietary zinc occurs mainly in
the small intestine, and zinc uptake can be competitive with that of
iron. Zinc is excreted in feces, urine and sweat. Copper or iron
deficiency, anemia, bone and joint pathology, loss of hair color may
be present. SOURCE: herring, egg yolks, corn, wheat germ, and
legumes. The RDA is 3-30mg/day, depending on age and status. High
hair zinc may be caused by slow hair growth due to a defect in
protein metabolism, or long-term, chronic exposure. Check for zinc
deficiency symptoms such as delayed wound healing. Symptoms of zinc
overload are impaired iron, copper and phosphorus metabolism.
THERAPEUTIC CONSIDERATION: Elevated zinc levels are almost always
linked to other heavy metal toxicity which isn’t always reflected in
the hair. A
urine challenge test is recommended to evaluate
further metal toxicity. Symptoms of zinc overload are similar to
zinc deficiency symptoms, causing immune dysfunction.
|